Conservation of Genetically-Embedded Virus Assembly Instructions: A Novel Route to Antiviral Therapy

Many single-stranded RNA viruses, including major viral pathogens, present RNA-encoded virus assembly instructions (VAIs) within their genetic message that can be isolated from the genetic code and repurposed for the design of virus-like particles. These VAIs rely on multiple dispersed RNA secondary...

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Detalhes bibliográficos
Main Authors: Reidun Twarock, Peter G. Stockley, Richard J. Bingham, Eric C. Dykeman, Pierre-Philippe Dechant
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-06-01
Colecção:Proceedings
Assuntos:
viral assembly
packaging signals
viral evolution
antiviral therapy
multiscale models
RNA SELEX
Acesso em linha:https://www.mdpi.com/2504-3900/50/1/87
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