Cited2 regulates proliferation and survival in young and old mouse cardiac stem cells

Abstract Background Cardiac stem cells (CSCs) exhibit age-dependent characteristics. Cited2 has been implicated in the regulation of heart development; however, there is little known about how Cited2 affects CSC aging. Results Cited2 mRNA and protein level was downregulated in aging heart tissue and...

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Detalhes bibliográficos
Main Authors: Qiong Wu, Qin Liu, Jinxi Zhan, Qian Wang, Daxiu Zhang, Shuangli He, Shiming Pu, Zuping Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-07-01
Colecção:BMC Molecular and Cell Biology
Assuntos:
Cardiac stem cells
Cited2
Aging
Apoptosis
Proliferation
Acesso em linha:http://link.springer.com/article/10.1186/s12860-019-0207-2
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