Overexpression of Toll-Like Receptor 4 Contributes to Phagocytosis of Salmonella Enterica Serovar Typhimurium via Phosphoinositide 3-Kinase Signaling in Sheep

Background/Aims: Phagocytosis of bacteria by monocytes/macrophages can trigger the immune response and the clearance of bacteria. This innate immune response involves Toll-like receptor 4 (TLR4). However, much remains unknown about the mechanism of TLR4-regulated phagocytosis of Salmonella enterica...

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Hauptverfasser: Sutian Wang, Shoulong Deng, Yang Cao, Rui Zhang, Zhixian Wang, Xiaojing Jiang, Jiahao Wang, Xiaosheng Zhang, Jinlong Zhang, Guoshi Liu, Zhengxing  Lian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Schriftenreihe:Cellular Physiology and Biochemistry
Schlagworte:
Transgenic sheep
Toll-like receptor 4
Phagocytosis
PI3K
Scavenger receptor
Online Zugang:https://www.karger.com/Article/FullText/493032
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