CD38 Expression by Antigen-Specific CD4 T Cells Is Significantly Restored 5 Months After Treatment Initiation Independently of Sputum Bacterial Load at the Time of Tuberculosis Diagnosis

T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by Mycobacterium tuberculosis (Mtb). Reciprocally, their modulation may be used to assess antibiotic treatment efficacy and eventually attest disease re...

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Main Authors: Hellen Hiza, Jerry Hella, Ainhoa Arbués, Mohamed Sasamalo, Veronica Misana, Jacques Fellay, Sébastien Gagneux, Klaus Reither, Damien Portevin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Medicine
Assuntos:
tuberculosis
treatment monitoring
CD38
CD27
TAM-TB
MBLA
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fmed.2022.821776/full
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