COS-7-based model: methodological approach to study John Cunningham virus replication cycle

Abstract John Cunningham virus (JCV) is a human neurotropic polyomavirus whose replication in the Central Nervous System (SNC) induces the fatal demyelinating disease, progressive multifocal leukoencephalopathy (PML). JCV propagation and PML investigation have been severely hampered by the lack of a...

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Autors principals: C. Prezioso, D. Scribano, D. M. Rodio, C. Ambrosi, M. Trancassini, A. T. Palamara, V. Pietropaolo
Format: Artigo
Idioma:Inglês
Publicat: BMC 2018-02-01
Col·lecció:Virology Journal
Matèries:
COS-7 cell line
JCV
Infection
Q-PCR
VP1
Western blot
Accés en línia:http://link.springer.com/article/10.1186/s12985-018-0939-1
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