Case report: mutation analysis of primary pulmonary lymphoepithelioma-like carcinoma via whole-exome sequencing

Abstract Background Primary pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare tumor subtype accounting for around 0.9% of lung cancers. At present, research on LELC mainly focuses on pathological diagnosis, while the molecular mutation landscape is still unclear. Case presentation A 72-yea...

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Main Authors: Hong Xuan, Chai Zhengjun, Han Yang, Chen Guohan
Format: Artigo
Jezik:Inglês
Izdano: BMC 2019-06-01
Serija:Diagnostic Pathology
Teme:
Lymphoepithelioma-like carcinoma
Lung cancer
Whole-exome sequencing
Gene mutation
Tumor mutation burden
Online dostop:http://link.springer.com/article/10.1186/s13000-019-0811-7
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