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Novel venom-based peptides (P13 and its derivative—M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways

Abstract Background In our previous study, a venom-based peptide named Gonearrestide (also named P13) was identified and demonstrated with an effective inhibition in the proliferation of colon cancer cells. In this study, we explored if P13 and its potent mutant M6 could promote the proliferation of...

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Main Authors: Rui Ma, Zhili Ren, Bin Li, Shirley W. I. Siu, Guokai Chen, Hang Fai Kwok
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-06-01
Colecção:Stem Cell Research & Therapy
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Acesso em linha:http://link.springer.com/article/10.1186/s13287-020-01766-9
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