HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice

Inflammatory bowel disease (IBD) is a chronic inflammatory disease, in which the intestinal epithelium loses its barrier function. Given the existence of the oxygen gradient in the intestinal epithelium and that inflammation further contributes to the tissue hypoxia, we investigated the role of hypo...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Young-Eun Kim, Minji Lee, Hyejung Gu, Jeongwoo Kim, Seongju Jeong, Sujin Yeo, You Jeong Lee, Sin-Hyeog Im, Young-Chul Sung, Hak Jae Kim, Irving L. Weissman, G-One Ahn
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists 2018-07-01
Serie:Disease Models & Mechanisms
Ämnen:
Hypoxia-inducible factor
Myeloid cells
Dextran sodium sulfate
Colitis
Länkar:http://dmm.biologists.org/content/11/7/dmm033241
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk