HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice

Inflammatory bowel disease (IBD) is a chronic inflammatory disease, in which the intestinal epithelium loses its barrier function. Given the existence of the oxygen gradient in the intestinal epithelium and that inflammation further contributes to the tissue hypoxia, we investigated the role of hypo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Young-Eun Kim, Minji Lee, Hyejung Gu, Jeongwoo Kim, Seongju Jeong, Sujin Yeo, You Jeong Lee, Sin-Hyeog Im, Young-Chul Sung, Hak Jae Kim, Irving L. Weissman, G-One Ahn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2018-07-01
Cyfres:Disease Models & Mechanisms
Pynciau:
Hypoxia-inducible factor
Myeloid cells
Dextran sodium sulfate
Colitis
Mynediad Ar-lein:http://dmm.biologists.org/content/11/7/dmm033241
Tagiau: Ychwanegu Tag
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