Rosmarinic Acid Attenuates the Lipopolysaccharide-Provoked Inflammatory Response of Vascular Smooth Muscle Cell via Inhibition of MAPK/NF-κB Cascade

Rosmarinic acid (RA) is a phenolic compound that has several bioactivities, such as anti-inflammatory and antioxidant activities. Here, we further investigate the anti-inflammatory effect of RA on rat A7r5 aortic smooth muscle cells with exposure to lipopolysaccharide (LPS). Our findings showed that...

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Detalhes bibliográficos
Principais autores: Ching-Pei Chen, You-Cian Lin, Yu-Hui Peng, Han-Min Chen, Jiun-Tsai Lin, Shao-Hsuan Kao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-03-01
coleção:Pharmaceuticals
Assuntos:
rosmarinic acid
vascular smooth muscle cell
proinflammatory response
mitogen-activated protein kinase
NF-κB
Acesso em linha:https://www.mdpi.com/1424-8247/15/4/437
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