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Gsk3 Signalling and Redox Status in Bipolar Disorder: Evidence from Lithium Efficacy

Objective. To discuss the link between glycogen synthase kinase-3 (GSK3) and the main biological alterations demonstrated in bipolar disorder (BD), with special attention to the redox status and the evidence supporting the efficacy of lithium (a GSK3 inhibitor) in the treatment of BD. Methods. A lit...

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Autors principals: Antonina Luca, Carmela Calandra, Maria Luca
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Limited 2016-01-01
Col·lecció:Oxidative Medicine and Cellular Longevity
Accés en línia:http://dx.doi.org/10.1155/2016/3030547
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