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Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model

Rational design of multi-targeted drug combinations is a promising strategy to tackle the drug resistance problem for many complex disorders. A drug combination is usually classified as synergistic or antagonistic, depending on the deviation of the observed combination response from the expected eff...

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Detaylı Bibliyografya
Asıl Yazarlar: Bhagwan Yadav, Krister Wennerberg, Tero Aittokallio, Jing Tang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2015-01-01
Seri Bilgileri:Computational and Structural Biotechnology Journal
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2001037015000422
Etiketler: Etiketle
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