Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma

Abstract Lysine demethylase 5C (KDM5C) is a member of the KDM family of demethylases and has been reported as a cancer driver. This study aimed to probe the function of KDM5C in the development of liver hepatocellular carcinoma (LIHC) and the molecules of action. According to data from publicly acce...

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Bibliographic Details
Main Authors: Xu Qian, Zhong‐Ming Bao, Dan Yao, Yang Shi
Format: Artigo
Language:Inglês
Published: Wiley 2022-05-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
ITIH1
liver hepatocellular carcinoma
lysine demethylase 5C
PI3K/AKT signaling pathway
Online Access:https://doi.org/10.1002/kjm2.12501
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