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An Improved Method for Modeling Voltage-Gated Ion Channels at Atomic Accuracy Applied to Human Cav Channels
Summary: Voltage-gated ion channels (VGICs) are associated with hundreds of human diseases. To date, 3D structural models of human VGICs have not been reported. We developed a 3D structural integrity metric to rank the accuracy of all VGIC structures deposited in the PDB. The metric revealed inaccur...
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Main Authors: | , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Elsevier
2018-05-01
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Serier: | Cell Reports |
Online adgang: | http://www.sciencedirect.com/science/article/pii/S2211124718305539 |
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