Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer

Abstract Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used chemotherapeutic, induces neuronal mitochondrial dysfunction in vivo and in vitro. Astrocytes are key players in supporting ne...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Krystal English, Andrew Shepherd, Ndidi-Ese Uzor, Ronnie Trinh, Annemieke Kavelaars, Cobi J. Heijnen
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-03-01
Colecção:Acta Neuropathologica Communications
Assuntos:
Astrocytes
Cortical neurons
Mitochondria
Cisplatin
Miro-1
Acesso em linha:http://link.springer.com/article/10.1186/s40478-020-00897-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados