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Framework for interpretation of trypsin-antitrypsin imbalance and genetic heterogeneity in pancreatitis
Early intracellular premature trypsinogen activation was interpreted as the key initiator of pancreatitis. When the balance in the homeostasis of trypsin and antitrypsin system is disequilibrated, elevated aggressive enzymes directly attack the pancreatic tissue, which leads to pancreatic destructio...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Wolters Kluwer Medknow Publications
2015-01-01
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Colecção: | The Saudi Journal of Gastroenterology |
Assuntos: | |
Acesso em linha: | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2015;volume=21;issue=4;spage=198;epage=207;aulast=Lin |
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