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Regulators associated with clinical outcomes revealed by DNA methylation data in breast cancer.

The regulatory architecture of breast cancer is extraordinarily complex and gene misregulation can occur at many levels, with transcriptional malfunction being a major cause. This dysfunctional process typically involves additional regulatory modulators including DNA methylation. Thus, the interplay...

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Detalhes bibliográficos
Main Authors: Matthew H Ung, Frederick S Varn, Shaoke Lou, Chao Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-05-01
Colecção:PLoS Computational Biology
Acesso em linha:http://europepmc.org/articles/PMC4440643?pdf=render
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