CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants

Summary: Non-coding DNA variants (NCVs) impact gene expression by altering binding sites for regulatory complexes. New high-throughput methods are needed to characterize the impact of NCVs on regulatory complexes. We developed CASCADE (Customizable Approach to Survey Complex Assembly at DNA Elements...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: David Bray, Heather Hook, Rose Zhao, Jessica L. Keenan, Ashley Penvose, Yemi Osayame, Nima Mohaghegh, Xiaoting Chen, Sreeja Parameswaran, Leah C. Kottyan, Matthew T. Weirauch, Trevor Siggers
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2022-02-01
Col·lecció:Cell Genomics
Matèries:
cofactor
transcription factor
recruitment
single-nucleotide polymorphism
screen
logo
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2666979X22000155
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars