LNC473 Regulating APAF1 IRES-Dependent Translation via Competitive Sponging miR574 and miR15b: Implications in Colorectal Cancer

A growing number of studies have focused on the involvement of non-coding RNAs (ncRNAs) in the internal ribosome entry site (IRES)-mediated translation in tumorigenesis; however, the underlying mechanisms in colorectal cancer (CRC) remain elusive. In this study, we show that LINC00473 (LNC473) exert...

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Hauptverfasser: Huizhe Wu, Xiaoyun Hu, Yalun Li, Qiuchen Chen, Tong Sun, Yun Qiao, Wenyan Qin, Zhikun Wu, Boshi Fu, Haishan Zhao, Rui Zhang, Minjie Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020-09-01
Schriftenreihe:Molecular Therapy: Nucleic Acids
Schlagworte:
LNC473
IRES-mediated translation
miR574-5p
miR15b-5p
ceRNA
APAF1
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2162253120301980
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