IL-33/ST2 correlates with severity of haemorrhagic fever with renal syndrome and regulates the inflammatory response in Hantaan virus-infected endothelial cells.

Hantaan virus (HTNV) causes a severe lethal haemorrhagic fever with renal syndrome (HFRS) in humans. Despite a limited understanding of the pathogenesis of HFRS, the importance of the abundant production of pro-inflammatory cytokines has been widely recognized. Interleukin 33 (IL-33) has been demons...

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Main Authors: Yusi Zhang, Chunmei Zhang, Ran Zhuang, Ying Ma, Yun Zhang, Jing Yi, Angang Yang, Boquan Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-02-01
Colecção:PLoS Neglected Tropical Diseases
Acesso em linha:http://europepmc.org/articles/PMC4319827?pdf=render
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