Mesenchymal Stem Cells and Extracellular Vesicles Derived from Canine Adipose Tissue Ameliorates Inflammation, Skin Barrier Function and Pruritus by Reducing JAK/STAT Signaling in Atopic Dermatitis

Canine atopic dermatitis (AD) is a common chronic inflammatory skin disorder resulting from imbalance between T lymphocytes. Current canine AD treatments use immunomodulatory drugs, but some of the dogs have limitations that do not respond to standard treatment, or relapse after a period of time. Th...

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Detalhes bibliográficos
Main Authors: Sung Youl Kim, Tae Hong Yoon, Jungtae Na, Seong Joon Yi, Yunseok Jin, Minji Kim, Tae-Ho Oh, Tae-Wook Chung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:International Journal of Molecular Sciences
Assuntos:
atopic dermatitis
canine
mesenchymal stem cell
extracellular vesicle
inflammation
skin barrier function
Acesso em linha:https://www.mdpi.com/1422-0067/23/9/4868
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