Early Paradoxical Increase of Dopamine: A Neurochemical Study of Olfactory Bulb in Asymptomatic and Symptomatic MPTP Treated Monkeys

Parkinson’s disease (PD) is a neurodegenerative disease with both motor and non-motor manifestations. Hyposmia is one of the early non-motor symptoms, which can precede motor symptoms by several years. The relationship between hyposmia and PD remains elusive. Olfactory bulb (OB) pathology shows an i...

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Detalhes bibliográficos
Main Authors: Christian Pifl, Harald Reither, Natalia Lopez-Gonzalez del Rey, Carmen Cavada, Jose A. Obeso, Javier Blesa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-05-01
Colecção:Frontiers in Neuroanatomy
Assuntos:
olfactory bulb
MPTP
dopamine
noradrenaline
serotonin
amino acid neurotransmitters
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fnana.2017.00046/full
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