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New insights emerge as antibody repertoire diversification meets chromosome conformation [version 1; peer review: 3 approved]

Vast repertoires of unique antigen receptors are created in developing lymphocytes. The antigen receptor loci contain many variable (V), diversity (D), and joining (J) gene segments that are arrayed across very large genomic expanses and are joined to form variable-region exons. This process creates...

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Detalhes bibliográficos
Main Authors: Amy L. Kenter, Ann J. Feeney
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Ltd 2019-03-01
Colecção:F1000Research
Acesso em linha:https://f1000research.com/articles/8-347/v1
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