Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism.

Intracellular nicotinamide phosphoribosyltransferase (iNAMPT) in neuron has been known as a protective factor against cerebral ischemia through its enzymatic activity, but the role of central extracellular NAMPT (eNAMPT) is not clear. Here we show that eNAMPT protein level was elevated in the ischem...

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Autores principales: Bing Zhao, Meng Zhang, Xue Han, Xia-Yan Zhang, Qiong Xing, Xu Dong, Qiao-Juan Shi, Peng Huang, Yun-Bi Lu, Er-Qing Wei, Qiang Xia, Wei-Ping Zhang, Chun Tang
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3877362?pdf=render
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