Metabonomic Profiling Reveals Difference in Altered Metabolic Pathways Between Chronic Kidney Disease and High-Fat-Induced Insulin Resistance in Rats

Background/Aims: Chronic kidney disease (CKD) is closely correlated with the development of insulin resistance (IR). Until now, the underlying molecular mechanisms remain to be elucidated. This study aimed to identify metabolites and molecular pathways unique to CKD-induced IR. Methods: Ultra-perfor...

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Detalhes bibliográficos
Main Authors: Zhuo Xu, Li Zhang, Jiao Li, Yang Zhao, Xiangmei Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Karger Publishers 2018-08-01
Colecção:Kidney & Blood Pressure Research
Assuntos:
Chronic kidney disease
5/6 Nephrectomy
Insulin resistance
Metabonomic profiling
Acesso em linha:https://www.karger.com/Article/FullText/492247
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