Neurodegenerative diseases as proteinopathies-driven immune disorders

In the pathophysiology of neurodegenerative disorders, the role of misfolded protein deposition leading to neurodegeneration has been primarily discussed. In the last decade, however, it has been proposed a parallel involvement of innate immune activation, chronic inflammation and adaptive immunity...

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Main Authors: Fausta Ciccocioppo, Giuseppina Bologna, Eva Ercolino, Laura Pierdomenico, Pasquale Simeone, Paola Lanuti, Damiana Pieragostino, Piero Del Boccio, Marco Marchisio, Sebastiano Miscia
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Assuntos:
adaptive immunity; choroid plexus; immunotherapy; innate immunity; neurodegenerative diseases; neuroinflammation; proteinopathies
Acceso en liña:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=5;spage=850;epage=856;aulast=Ciccocioppo
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