Transplantation of erythropoietin gene-modified neural stem cells improves the repair of injured spinal cord

The protective effects of erythropoietin on spinal cord injury have not been well described. Here, the eukaryotic expression plasmid pcDNA3.1 human erythropoietin was transfected into rat neural stem cells cultured in vitro. A rat model of spinal cord injury was established using a free falling obje...

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Main Authors: Min-fei Wu, Shu-quan Zhang, Rui Gu, Jia-bei Liu, Ye Li, Qing-san Zhu
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Medknow Publications 2015-01-01
Series:Neural Regeneration Research
Assuntos:
nerve regeneration; spinal cord injury; neural stem cells; erythropoietin; motor function; subarachnoid cavity; transplantation; injury; recovery; neural regeneration
Acceso en liña:http://www.nrronline.org/article.asp?issn=1673-5374;year=2015;volume=10;issue=9;spage=1483;epage=1490;aulast=Wu
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