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Do Increased Doses to Stem-Cell Niches during Radiation Therapy Improve Glioblastoma Survival?

Background and Purpose. The reasons for the inevitable glioblastoma recurrence are yet understood. However, recent data suggest that tumor cancer stem cells (CSCs) in the stem-cell niches, with self-renewing capacities, might be responsible for tumor initiation, propagation, and recurrence. We aimed...

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Detalhes bibliográficos
Main Authors: Sebastian Adeberg, Semi Ben Harrabi, Nina Bougatf, Denise Bernhardt, Angela Mohr, Juliane Rieber, Christian Koelsche, Stefan Rieken, Juergen Debus
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2016-01-01
Colecção:Stem Cells International
Acesso em linha:http://dx.doi.org/10.1155/2016/8793462
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