Neuroendocrine differentiation distinguishes basaloid variant of lung squamous cell carcinoma

Abstract Background Neuroendocrine (NE) differentiation is widely studied in non-small cell lung carcinomas (NSCLC) however, its significance remains unclear in basaloid squamous cell carcinomas (B-SqCC). This study aims to assess the extent of NE differentiation in B-SqCC and characterize the under...

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Detalhes bibliográficos
Main Authors: Kianoosh Keyhanian, William J. Phillips, Benjamin S. Yeung, Marcio Gomes, Bryan Lo, Harmanjatinder S. Sekhon
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
Colecção:Diagnostic Pathology
Assuntos:
Basaloid squamous cell carcinoma
Neuroendocrine differentiation
Gene expression
Immunohistochemistry
NOTCH
Acesso em linha:https://doi.org/10.1186/s13000-022-01223-6
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