CircSLNN: Identifying RBP-Binding Sites on circRNAs via Sequence Labeling Neural Networks

The interactions between RNAs and RNA binding proteins (RBPs) are crucial for understanding post-transcriptional regulation mechanisms. A lot of computational tools have been developed to automatically predict the binding relationship between RNAs and RBPs. However, most of the methods can only pred...

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Autori principali: Yuqi Ju, Liangliang Yuan, Yang Yang, Hai Zhao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-11-01
Serie:Frontiers in Genetics
Soggetti:
RNA–protein binding sites
sequence labeling
convolutional neural network
bidirectional LSTM neural network
deep learning
Accesso online:https://www.frontiersin.org/article/10.3389/fgene.2019.01184/full
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