An Efficient Protocol for the Synthesis of O-Fluoroalkylisoureas through Copper-Catalysed, Three-Component Reaction of Cyan­amides, Fluoroalcohols and Diaryliodonium Triflates

Abstract A copper-catalysed, three-component reaction involving cyan­amides, fluoroalcohols and diaryliodonium triflates is disclosed for the synthesis of O-fluoroalkylisoureas. Various O-fluoroalkylisoureas were obtained in good yields by using simple and readily available substrates. Moreover, C–H...

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Detalhes bibliográficos
Main Authors: Jihui Li, Weiguang Yu, Yifeng Hou, Wenxing Fu, Shuying Xu, Yucang Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2017-03-01
Colecção:SynOpen
Assuntos:
copper-catalysis
three-component reaction
o-fluoro­alkylisourea
2-alkoxybenzimidazole
c–h activation
Acesso em linha:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1590828
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