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USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components

The ubiquitin specific protease 39 (USP39) interacts with the transcription factor and cytoplasmic regulator of planar cell polarity (PCP), Grainyheadlike 3 (Grhl3). USP39-dependent PCP gene upregulation contributes to epithelial morphogenesis.

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Autori principali: Chiharu Kimura-Yoshida, Kyoko Mochida, Shin-Ichiro Kanno, Isao Matsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2022-04-01
Serie:Communications Biology
Accesso online:https://doi.org/10.1038/s42003-022-03254-7
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