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The Role of Heterotypic DENV-specific CD8+T Lymphocytes in an Immunocompetent Mouse Model of Secondary Dengue Virus Infection

Dengue is the most prevalent arthropod-borne viral disease worldwide and is caused by the four dengue virus serotypes (DENV-1-4). Sequential heterologous DENV infections can be associated with severe disease manifestations. Here, we present an immunocompetent mouse model of secondary DENV infection...

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Detalhes bibliográficos
Main Authors: Laura B. Talarico, Juan P. Batalle, Alana B. Byrne, Jorge M. Brahamian, Adrián Ferretti, Ayelén G. García, Aldana Mauri, Carla Simonetto, Diego R. Hijano, Andrea Lawrence, Patricio L. Acosta, Mauricio T. Caballero, Yésica Paredes Rojas, Lorena I. Ibañez, Guillermina A. Melendi, Félix A. Rey, Elsa B. Damonte, Eva Harris, Fernando P. Polack
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017-06-01
Colecção:EBioMedicine
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396417301883
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