Genistein inhibits prostate cancer cell growth by targeting miR-34a and oncogenic HOTAIR.

OBJECTIVE:Genistein is a soy isoflavone that has antitumor activity both in vitro and in vivo. It has been shown that genistein inhibits many type of cancers including prostate cancer (PCa) by regulating several cell signaling pathways and microRNAs (miRNAs). Recent studies suggest that the long non...

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Autores principales: Takeshi Chiyomaru, Soichiro Yamamura, Shinichiro Fukuhara, Hirofumi Yoshino, Takashi Kinoshita, Shahana Majid, Sharanjot Saini, Inik Chang, Yuichiro Tanaka, Hideki Enokida, Naohiko Seki, Masayuki Nakagawa, Rajvir Dahiya
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3731248?pdf=render
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