An approach for elucidating dermal fibroblast dedifferentiation in amphibian limb regeneration

Abstract Urodele amphibians, Pleurodeles waltl and Ambystoma mexicanum, have organ-level regeneration capability, such as limb regeneration. Multipotent cells are induced by an endogenous mechanism in amphibian limb regeneration. It is well known that dermal fibroblasts receive regenerative signals...

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Detalhes bibliográficos
Main Authors: Akira Satoh, Rena Kashimoto, Ayaka Ohashi, Saya Furukawa, Sakiya Yamamoto, Takeshi Inoue, Toshinori Hayashi, Kiyokazu Agata
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:Zoological Letters
Assuntos:
Pde4b
Limb regeneration
Pleurodels waltl
Ambystoma mexicanum
Dedifferentiation
Reprogramming
Acesso em linha:https://doi.org/10.1186/s40851-022-00190-6
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