Protective Immunity in Mice Immunized With P. vivax MSP119-Based Formulations and Challenged With P. berghei Expressing PvMSP119

The lack of continuous in vitro cultures has been an obstacle delaying pre-clinical testing of Plasmodium vivax vaccine formulations based on known antigens. In this study, we generated a model to test available formulations based on the P. vivax MSP119 antigen. The Plasmodium berghei strains ANKA a...

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Detalhes bibliográficos
Main Authors: Irina Dobrescu, Tarsila Mendes de Camargo, Alba Marina Gimenez, Oscar Murillo, Kelly Nazaré da Silva Amorim, Claudio Romero Farias Marinho, Irene Silva Soares, Silvia Beatriz Boscardin, Daniel Youssef Bargieri
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-02-01
Colecção:Frontiers in Immunology
Assuntos:
Plasmodium vivax
Plasmodium berghei
vaccines
MSP119
mouse model
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2020.00028/full
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