Anaplastic Lymphoma Kinase Is a Regulator of Alcohol Consumption and Excitatory Synaptic Plasticity in the Nucleus Accumbens Shell

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase recently implicated in biochemical, physiological, and behavioral responses to ethanol. Thus, manipulation of ALK signaling may represent a novel approach to treating alcohol use disorder (AUD). Ethanol induces adaptations in glutamaterg...

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Detalhes bibliográficos
Main Authors: Regina A. Mangieri, Esther Y. Maier, Tavanna R. Buske, Amy W. Lasek, Richard A. Morrisett
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-08-01
Colecção:Frontiers in Pharmacology
Assuntos:
electrophysiology
operant self-administration
glutamate
two-bottle choice
mice
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fphar.2017.00533/full
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