The dynamic alteration of transcriptional regulation by crucial TFs during tumorigenesis of gastric cancer

Abstract Background The mechanisms of Gastric cancer (GC) initiation and progression are complicated, at least partly owing to the dynamic changes of gene regulation during carcinogenesis. Thus, investigations on the changes in regulatory networks can improve the understanding of cancer development...

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Main Authors: Beiqin Yu, Wentao Dai, Li Pang, Qingqing Sang, Fangyuan Li, Junxian Yu, Haoran Feng, Jianfang Li, Junyi Hou, Chao Yan, Liping Su, Zhenggang Zhu, Yuan-Yuan Li, Bingya Liu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:Molecular Medicine
Assuntos:
Gastric cancer
Differential co-expression analysis
Gene regulatory network
Differential regulation analysis
Transcription factors
Acesso em linha:https://doi.org/10.1186/s10020-022-00468-7
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