The analysis of novel microRNA mimic sequences in cancer cells reveals lack of specificity in stem-loop RT-qPCR-based microRNA detection

Abstract Objective MicroRNAs are frequently downregulated in cancer, and restoring expression has tumour suppressive activity in tumour cells. Our recent phase I clinical trial investigated microRNA-based therapy in patients with malignant pleural mesothelioma. Treatment with TargomiRs, microRNA mim...

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Main Authors: Patrick Winata, Marissa Williams, Eileen McGowan, Najah Nassif, Nico van Zandwijk, Glen Reid
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-11-01
Colecção:BMC Research Notes
Assuntos:
MicroRNA
Mimic
RT-qPCR
TargomiR
MesomiR
Acesso em linha:http://link.springer.com/article/10.1186/s13104-017-2930-0
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