Increased glutathione utilization augments tumor cell proliferation in Waldenstrom Macroglobulinemia

Metabolic reprogramming is a hallmark of cancer cells. In Waldenstrom Macroglobulinemia (WM), the infiltration of IgM-secreting lymphoplamacytic cells into the bone marrow (BM) could shift the homeostasis of proteins and metabolites towards a permissive niche for tumor growth. Here, we investigated...

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Main Authors: Shahrzad Jalali, Jie Shi, Alex Buko, Nagib Ahsan, Jonas Paludo, Makayla Serres, Linda E. Wellik, Jithma Abeykoon, HyoJin Kim, Xinyi Tang, Zhi-Zhang Yang, Anne J. Novak, Thomas E. Witzig, Stephen M. Ansell
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020-09-01
Serija:Redox Biology
Teme:
Waldenstrom Macroglobulinemia
Metabolism
Glutathione
Online dostop:http://www.sciencedirect.com/science/article/pii/S2213231720308624
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