CDX2-induced intestinal metaplasia in human gastric organoids derived from induced pluripotent stem cells

Summary: Intestinal metaplasia is related to gastric carcinogenesis. Previous studies have suggested the important role of CDX2 in intestinal metaplasia, and several reports have shown that the overexpression of CDX2 in mouse gastric mucosa caused intestinal metaplasia. However, no study has examine...

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Main Authors: Takahiro Koide, Michiyo Koyanagi-Aoi, Keiichiro Uehara, Yoshihiro Kakeji, Takashi Aoi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-05-01
Colecção:iScience
Assuntos:
Biological sciences
Cell biology
Stem cells research
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004222005855
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