Parallel Evaluation of Polyethylene Glycol Conformal Coating and Alginate Microencapsulation as Immunoisolation Strategies for Pancreatic Islet Transplantation

Pancreatic islet transplantation improves metabolic control and prevents complications in patients with brittle type 1 diabetes (T1D). However, chronic immunosuppression is required to prevent allograft rejection and recurrence of autoimmunity. Islet encapsulation may eliminate the need for immunosu...

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Detalhes bibliográficos
Main Authors: Teresa De Toni, Aaron A. Stock, Floriane Devaux, Grisell C. Gonzalez, Kailyn Nunez, Jessica C. Rubanich, Susan A. Safley, Collin J. Weber, Noel M. Ziebarth, Peter Buchwald, Alice A. Tomei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Bioengineering and Biotechnology
Assuntos:
alginate
polyethylene glycol
capsules
type 1 diabetes
encapsulation
transplantation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fbioe.2022.886483/full
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