CD73 in small extracellular vesicles derived from HNSCC defines tumour‐associated immunosuppression mediated by macrophages in the microenvironment

Abstract Research on tumour cell‐derived small extracellular vesicles (sEVs) that regulate tumour microenvironment (TME) has provided strategies for targeted therapy of head and neck squamous cell carcinoma (HNSCC). Herein, we demonstrated that sEVs derived from HNSCC cancer cells carried CD73 (sEVs...

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Detalhes bibliográficos
Main Authors: Tingwei Lu, Zhen Zhang, Jianjun Zhang, Xinhua Pan, Xueqin Zhu, Xu Wang, Zhihui Li, Min Ruan, Huasheng Li, Wantao Chen, Ming Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-05-01
Colecção:Journal of Extracellular Vesicles
Assuntos:
anti‐PD‐1 therapy
CD73
head and heck squamous cell carcinoma
macrophage
small extracellular vesicle
Acesso em linha:https://doi.org/10.1002/jev2.12218
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