Organotypic Co-Cultures as a Novel 3D Model for Head and Neck Squamous Cell Carcinoma

<i>Background</i>: Head and neck squamous cell carcinomas (HNSCC) are phenotypically and molecularly heterogeneous and frequently develop therapy resistance. Reliable patient-derived 3D tumor models are urgently needed to further study the complex pathogenesis of these tumors and to over...

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Main Authors: Luca Engelmann, Julia Thierauf, Natalia Koerich Laureano, Hans-Juergen Stark, Elena-Sophie Prigge, Dominik Horn, Kolja Freier, Niels Grabe, Chao Rong, Philippe Federspil, Karim Zaoui, Peter K. Plinkert, Nicole Rotter, Magnus von Knebel Doeberitz, Jochen Hess, Annette Affolter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
Colecção:Cancers
Assuntos:
HNSCC
3D organotypic co-culture model
invasion
HPV
Acesso em linha:https://www.mdpi.com/2072-6694/12/8/2330
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