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Inactivation of XPF Sensitizes Cancer Cells to Gemcitabine
Gemcitabine (2′, 2′-difluorodeoxycytidine; dFdC) is a deoxycytidine analog and is used primarily against pancreatic cancer. The cytotoxicity of gemcitabine is due to the inhibition of DNA replication. However, a mechanism of removal of the incorporated dFdC is largely unknown. In this report, we dis...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Hindawi Limited
2019-01-01
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| Colección: | Journal of Nucleic Acids |
| Acceso en línea: | http://dx.doi.org/10.1155/2019/6357609 |
| Etiquetas: |
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