Construction of in vitro 3-D model for lung cancer-cell metastasis study

Abstract Background Cancer metastasis is the main cause of mortality in cancer patients. However, the drugs targeting metastasis processes are still lacking, which is partially due to the short of effective in vitro model for cell invasion studies. The traditional 2-D culture method cannot reveal th...

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Main Authors: Rongrong Jiang, Jiechun Huang, Xiaotian Sun, Xianglin Chu, Fangrui Wang, Jie Zhou, Qihui Fan, Liewen Pang
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMC 2022-04-01
Sraith:BMC Cancer
Ábhair:
3-D model
Collagen hydrogel
Cancer metastasis
Drug screening
Microfluidic system
Rochtain Ar Líne:https://doi.org/10.1186/s12885-022-09546-9
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