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Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity

To find novel antitumor agents, a series of 1H-benzofuro[3,2-c]pyrazole derivatives 4a-e were designed and synthesized. The treatment of 6-methoxybenzofuran-3(2H)-one 3 with LiHMDS in anhydrous tetrahydrofuran (THF) followed by reaction with 3-substitued phenyl isothiocyanate gave the thioamide inte...

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Main Authors: Ying-Jie Cui, Long-Qian Tang, Cheng-Mei Zhang, Zhao-Peng Liu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-01-01
Colecção:Molecules
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Acesso em linha:http://www.mdpi.com/1420-3049/24/2/279
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