Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity

To find novel antitumor agents, a series of 1H-benzofuro[3,2-c]pyrazole derivatives 4a-e were designed and synthesized. The treatment of 6-methoxybenzofuran-3(2H)-one 3 with LiHMDS in anhydrous tetrahydrofuran (THF) followed by reaction with 3-substitued phenyl isothiocyanate gave the thioamide inte...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ying-Jie Cui, Long-Qian Tang, Cheng-Mei Zhang, Zhao-Peng Liu
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2019-01-01
Colección:Molecules
Materias:
privileged structure
pyrazoles
tubulin inhibitors
antitumor
antitumor agents
Acceso en línea:http://www.mdpi.com/1420-3049/24/2/279
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares