Cytotoxic effect of disulfiram/copper on human cervical cancer cell lines and LGR5-positive cancer stem-like cells

Abstract Background Tumor resistance is a global challenge for tumor treatment. Cancer stem cells (CSCs) are the main population of tumor cells for drug resistance. We have reported that high aldehyde dehydrogenase (ALDH) activity represents a functional marker for cervical CSCs. Here, we aimed at d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hao-Zhe Cao, Wen-Ting Yang, Peng-Sheng Zheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2022-05-01
Cyfres:BMC Cancer
Pynciau:
LGR5
Disulfiram
Copper
Cervical cancer
Cancer stem cell
Mynediad Ar-lein:https://doi.org/10.1186/s12885-022-09574-5
Tagiau: Ychwanegu Tag
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