Astragaloside IV Protects Rat Cardiomyocytes from Hypoxia-Induced Injury by Down-Regulation of miR-23a and miR-92a

Background/Aims: Astragaloside IV (AS-IV), a traditional Chinese medicine isolated from Astragalus membranaceus, has been shown to exert cardioprotective effect previously. This study aimed to reveal the effects of AS-IV on hypoxia-injured cardiomyocyte. Methods: H9c2 cells were treated with various...

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Bibliographic Details
Main Authors: Licheng Gong, Hong Chang, Jingze Zhang, Gongliang Guo, Jingwei Shi, Haiming Xu
Format: Artigo
Language:Inglês
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Astragaloside IV (AS-IV)
Myocardial infarction (MI)
H9c2 cell
miR-23a
miR-92a
Hypoxia
Online Access:https://www.karger.com/Article/FullText/493827
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