A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5

Abstract Background RNA-binding proteins (RBPs) and circular RNAs (circRNAs) play important roles in glioblastoma multiforme (GBM). Aerobic glycolysis is a metabolic characteristic of GBM. However, the roles of RBPs and circRNAs in aerobic glycolysis in GBM remain unclear. The aim of this study is t...

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Main Authors: Jian Song, Jian Zheng, Xiaobai Liu, Weiwei Dong, Chunqing Yang, Di Wang, Xuelei Ruan, Yubo Zhao, Libo Liu, Ping Wang, Mengyang Zhang, Yunhui Liu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-05-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
Glioblastoma multiforme
Aerobic glycolysis
ZCRB1
circHEATR5B
JMJD5
PKM2
Online adgang:https://doi.org/10.1186/s13046-022-02374-6
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